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Tirzepatide is pretty impressive. All the research I've seen so far hasn't reported any harmful effects.
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The FDA has approved tirzepatide/Zepbound for moderate to severe obstructive sleep apnea (OSA) in obese adults. The key evidence comes from two 52-week, double-blind, randomized controlled trials, totaling 469 adults with moderate to severe OSA and obesity. Baseline AHI was approximately 49.5–51.5 events per hour; the tirzepatide 10/15mg groups showed an additional reduction in AHI of about 20.0 and 23.8 events per hour compared to placebo, along with improvements in weight, hypoxic load, hs-CRP, and systolic blood pressure.