Hardware wallets, multi-signature, and social recovery—my current understanding of these is pretty rough: if you have little money and losing it wouldn't keep you awake, don't turn yourself into an operations engineer; if you have a lot of money and "even one wrong transfer hurts," then hardware wallets come first, at least to block everyday slips.

Beyond that, if your assets are starting to diversify, and you're doing frequent cross-chain/DeFi operations, multi-signature is more reasonable—otherwise, a single private key is both a ticket and a noose.
I'm quite conflicted about social recovery; it sounds gentle, but you first need to confirm whether your "friends" are another knife, because a changed relationship is more troublesome than a hacker.

By the way, retail investors complaining daily about validator/MEV ordering unfairness isn't without reason; honestly, on-chain, you might get jumped in line, so don't expect "convenient" signature methods to be foolproof and secure.
Anyway, my current approach is: cold storage for major assets + a small hot wallet for occasional use—don't gamble with yourself.