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Prelude Therapeutics Presents Preclinical Data from Development Candidate, PRT13722, a First-in-Class, Orally Bioavailable, Potent and Highly Selective KAT6A Degrader at American Association for Cancer Research (AACR) Annual Meeting 2026
Prelude Therapeutics announced preclinical data for PRT13722, a first-in-class, orally bioavailable KAT6A degrader for HR+/HER2- breast cancer. The data show potential for differentiated efficacy and safety, including complete responses as monotherapy in various models. Prelude aims to file an Investigational New Drug (IND) application by mid-2026 and initiate a clinical trial in the second half of 2026.