Takeda Exits Dementia Drug Partnership With Denali Therapeutics - Here's Why

Takeda has terminated its collaboration agreement with Denali Therapeutics for the co-development of DNL593, a treatment for frontotemporal dementia. Denali has regained full control over the therapy, and the decision was strategic, not related to efficacy or safety. Denali plans to announce biomarker results from the ongoing Phase 1/2 trial by the end of 2026.

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