# BitcoinOnchainDataAndUSMarketMicrostructure

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#BitcoinOnchainDataAndUSMarketMicrostructure
The sixteenth topic US desks use to run market strategy in 2026 is on-chain data. It’s now as standard as volume profile and order book heatmaps.
After the ETF era began, the edge shifted from “who has the best news” to “who can read the chain fastest.” US funds now have teams that treat Bitcoin’s ledger like a public order book.
Here are the 4 on-chain signals US institutions watch daily:
1. *Exchange + ETF Flows*: Glassnode, CryptoQuant, and Arkham are now in every Bloomberg terminal. The key metrics:
- Exchange Netflow: Coins moving to/from
BTC-0.76%
IBIT-1.79%
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