Global TradFi & Macroeconomics

Moderna and Merck announced Wednesday that their experimental mRNA cancer therapy demonstrated clinically meaningful improvement in treating high-risk melanoma patients, triggering a 177% surge in Moderna shares and a 12.6% rise in Merck stock. The combination therapy, called intismeran paired

According to reports, Moderna and Merck's experimental mRNA cancer therapy demonstrated clinical success in trials Wednesday, sending Moderna shares up 177% and Merck shares up 12.6%. The customized treatment, called intismeran, was tested in combination with Merck's cancer drug Keytruda in

Timefolio Asset Management's TIME US Dividend Dow Jones Active was delisted on the 19th for failing to maintain the required correlation coefficient with its benchmark index, despite generating excess returns. The delisting occurred one month after four ETFs including Korea Investment Trust Manageme

Stripe announced Wednesday it plans to acquire startup OpenRouter, expanding the fintech company deeper into the artificial intelligence model market. The New York Times reported the deal is valued at approximately $7.5 billion, citing a person familiar with the matter, with $1.5 billion allocated t

Tempus AI (TEM) shares climbed 22% on Wednesday after Merck and Moderna announced their Phase 3 INTerpath-001 study met its primary endpoint of keeping patients disease-free longer after surgery and a key secondary endpoint of reducing distant metastasis risk. The trial tested individualized mRNA th

According to Korea Exchange, Timefolio Asset Management's TIME U.S. Dividend Dow Jones Active ETF was delisted on August 19 for failing to maintain a correlation coefficient of 0.7 or higher with its benchmark index for three consecutive months. The product had delivered a 1-year return of 36.06% a

Chinese-listed stocks mostly rose today (August 19), with the Nasdaq China Golden Dragon Index up 1.52% and the WealthTech Index up 2.43%. Among major gainers, Kingsoft Cloud surged 14% and Astra Solar climbed over 7%. Beauty Semiconductor fell over 8% and ZTO Express dropped nearly 7%, leading

According to ChainCatcher, citing Gate market data, U.S. stock indices closed higher on August 19. The Dow Jones Industrial Average rose 119.71 points, up 0.22%, closing at 53,463.11. The S&P 500 gained 16.5 points, up 0.21%, at 7,708.26. The Nasdaq Composite Index increased 41.38 points, up 0.16%,

According to Argentina's Minister of Economy, Argentina approved a $6.4 billion large-scale investment incentive program on August 19 for TECPETROL's Los Toldos II oil project in Vaca Muerta.

VanEck reported Wednesday that Bitcoin is displaying eight of 12 capitulation indicators associated with major selloffs, with Bitcoin trading around $64,300, approximately 49% below its all-time high. The asset manager's analysis tracks conditions that reach extremes during market declines,

According to Bitwise CEO, Bitwise Hyperliquid ETF BHYP recorded trading volume exceeding $40 million on August 19, as announced via X platform.

Strategy (MSTR), Coinbase (COIN), Circle (CRCL), and BitMine (BMNR) surged on Wednesday, with MSTR climbing 11.95% to $103.58 and COIN rising 9.05% to $159.47. The rally tracked Bitcoin's move toward $70,000, which liquidated more than $1 billion in bearish crypto bets in a single hour. The U.S.

According to Jin10, on August 20, former President Trump urged the Federal Reserve to cut interest rates, stating that U.S. interest rates are too high. He claimed that each 1 percentage point rate cut would reduce costs by approximately $600 billion and criticized the current rate system as

SELLAS Life Sciences (SLS) stock rose 6% on Wednesday after Maxim Group analyst linked positive Moderna-Merck cancer vaccine data to the company's late-stage therapy program. Maxim argued that Moderna's Phase 3 melanoma trial success should support SELLAS if its own pivotal study succeeds. SELLAS's

On Wednesday (Aug 19), shares of SELLAS Life Sciences (SLS) rose 6% after Maxim Group tied Moderna and Merck's positive Phase 3 cancer vaccine results to the company's own late-stage program. According to Maxim, the success of Moderna's INTerpath-001 melanoma study—which met its primary endpoint of

According to Jin10, on August 20, Trump stated that the U.S. is constructing a record number of oil pipelines to reduce dependence on the Strait of Hormuz. He said the strait's strategic importance will decline as alternative supply routes emerge and the U.S. strengthens its control over the

Marvell Technology surged 8% on August 19 following an AI chip supply agreement with Google. Under the accord, Google has the option to purchase up to $12.2 billion in Marvell stock.

According to ChainCatcher, U.S. President Trump said today that the U.S. may continue to blockade the Strait of Hormuz.

President Trump stated today that the U.S. may reduce tariffs on Canada to levels applied to other nations, noting that Canada currently faces higher tariff rates.

The US Treasury auctioned $16 billion in new 20-year bonds at a yield of 5.204% on August 19 local time, according to the Treasury Department. The auction attracted weak demand, with the yield settling above market expectations. The 20-year bond remains the least popular and least traded among