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中信证券:GDF-15阻断剂有望获批治疗肿瘤恶病质
人民财讯3月24日电,中信证券研报称,GDF-15阻断剂有望治疗肿瘤恶病质、提升PD-(L)1疗效。肿瘤恶病质全球患者超100万人并且尚无针对性药物获批;约50-85%患者会对PD-(L)1产生耐药。GDF-15阻断剂已在II期临床概念性验证其在恶病质治疗中的疗效,并且目前已进入注册临床阶段,中信证券认为GDF-15阻断剂有望获批治疗肿瘤恶病质;GDF-15阻断剂联合PD-(L)1疗法在早期临床阶段展现出积极数据,目前已经开展多个II期临床试验,但仍需后续临床概念性验证。