Conocimiento previo de Hong Kong Stocks de Zhitong | Lanzamiento de la misión tripulada a la luna de EE. UU. La nave espacial despega | Director de la Agencia Internacional de Energía: La brecha en el suministro de petróleo en abril alcanzará el doble de la de marzo

【Today’s Headline】

**Director-General of the International Energy Agency: April oil supply shortfall will reach three times that of March

In a podcast released on Wednesday, the Director-General of the International Energy Agency, Fatih Birol, said the agency is considering whether it needs to urgently release oil reserves again, and urged governments of various countries to take other energy-saving measures, such as promoting remote work at home and lowering car speed limit standards.
Birol said in a program hosted by Nicolai Tangen, CEO of Norges Bank Investment Management, that: “The situation in April will be much more severe than in March.” He said that in March, oil supply was supported by cargoes already en route before the outbreak of the Iran war, so conditions were relatively more relaxed. He added: “The oil supply shortfall in April will reach twice that of March.”
Last month, including the United States, 32 member countries of the International Energy Agency released 400 million barrels of oil from emergency reserves to lower crude oil prices, marking the largest reserves release in the agency’s history.
Birol said: “We are assessing the market situation at a frequency of even every day, or even every hour, to decide whether to take further intervention measures.”

【Market Outlook】

**Overnight U.S. stocks rise collectively **Chip and memory concept stocks surge

As of the close of overnight trading,
the Dow Jones Industrial Average rose 224.23 points from the previous trading day, closing at 46565.74 points, an increase of 0.48%; the S&P 500 stock index rose 46.8 points to 6575.32 points, an increase of 0.72%; the Nasdaq Composite index rose 250.32 points to 21840.95 points, an increase of 1.16%.

Chip and memory concept stocks rose; Western Digital gained more than 10%, SanDisk rose more than 9%, Micron Technology and Intel rose more than 8%. The aluminum sector broadly rose; affected by the suspension of production at the Middle East’s largest aluminum company after a missile attack, Alcoa and Century Aluminum (share price hit a historical high) rose more than 8%. Nike’s share price fell 16% at the close, recording the largest single-day drop since June 2024.

Most popular China concept stocks closed higher; the Nasdaq China Golden Dragon Index rose 0.31%. Hang Seng Index ADRs rose; calculated proportionally, it closed at 25377.36 points, up 83.33 points, or 0.33%, from the close in Hong Kong.

On the New York Mercantile Exchange, the WTI crude oil futures month-ahead continuous contract fell $2.47 to $98.91 per barrel, a decline of 2.44%. COMEX gold futures month-ahead continuous contract rose $106.00, an increase of 2.27%, to $4784.6 per ounce.

【Hot Preview】

Vice President of Iran: “Currently, the Supreme Leader has not approved any negotiations”

According to a report from Iran’s Fars News Agency on April 1, Ali Nikzad, deputy chairman of Iran’s Islamic Parliament, delivered a public speech at a public gathering in Tavreš, Iran. He said that, under Iran’s constitution, decisions regarding war, peace, and any negotiations fall within the authority of Iran’s Supreme Leader: “Currently, the Supreme Leader has not approved any negotiations.” Market reports: several U.S. intelligence agencies recently assessed that the Iranian government currently has no intention to conduct substantive negotiations to end the conflict.

U.S. launches rocket for crewed mission around the Moon

In the evening of April 1 local time, NASA’s new-generation lunar rocket “Space Launch System” lifted off from the Kennedy Space Center in Florida to carry out the crewed lunar-orbit mission “Artemis 2.” This is the first time the United States has sent crew to the Moon since 1972.

Strategist: Prolongation of the Middle East conflict puts global fertilizer supply at risk

In a research report, analysts at ANZ Bank said that the prolonged Middle East conflict puts global fertilizer supply at risk. These strategists said the Middle East accounts for about 30% of global fertilizer trade and is an important hub for natural gas exports, and added that transport disruptions in the region have already started to affect fertilizer supply. They said energy shocks are also impacting fertilizer production costs, because nitrogen fertilizer is a natural-gas-intensive product. They pointed out that fertilizer-exporting countries such as China and Russia are implementing trade restrictions to ensure domestic supply, further tightening global supply. They added: “These disruptions will affect global food production, raising concerns about increased agricultural costs and production losses.”

SpaceX under Musk reportedly has submitted listing application

SpaceX, owned by Musk, has reportedly secretly submitted its initial public offering (IPO) application documents to the U.S. Securities and Exchange Commission (SEC), taking an important step that could make it one of the largest IPOs in history. According to people familiar with the matter, the satellite manufacturing and rocket launch company has submitted the listing application in a confidential manner. Earlier reports said SpaceX plans to raise about $40 billion to $80 billion through an IPO, and the company’s target valuation could be $1.75 trillion.

Contemporary Amperex Technology (03750) showcases energy-storage sodium-ion batteries for the first time 预计年内实现商业化

On the 1st, Contemporary Amperex Technology showcased energy-storage sodium-ion batteries for the first time. Their cycle life exceeds 15,000 cycles. The related energy-storage products can cover large energy-storage applications from 2 hours to 8 hours, as well as energy-storage use cases for intelligent computing data centers, with commercial deployment expected within the year. The sodium-ion batteries for energy storage shown this time adopt a platform-based design using the same housing as existing 587Ah lithium batteries, enabling system compatibility between lithium and sodium batteries.

Cerebo (00460)** and Beiou Sai Tu****(02315)**** reach strategic cooperation
Accelerate multi-domain innovative drug R&D such as weight loss through an AI-driven full human antibody development platform**

In a notification from the Zhitong Finance APP, Cerebo announced that the group and Beiou Sai Tu (Beijing) Pharmaceutical Technology Co., Ltd. have formally signed a strategic cooperation agreement. The two parties will, based on the principles of complementary strengths and professional synergy, and drawing on the group’s mature experience across the full industrial chain in areas such as drug development, large-scale manufacturing, and commercialization, combine the core technologies of Beiou Sai Tu’s industry-leading AI-driven full human antibody development platform to carry out joint R&D of innovative drugs in multiple high-potential disease areas such as weight loss, and establish a long-term stable, mutually beneficial and win-win cooperation relationship, jointly promoting the R&D and commercialization rollout of cutting-edge innovative drugs worldwide.

China Everbright Water (01857): Secures two water projects in Jiangsu; business portfolio continues to optimize; Yangtze River Delta layout deepens steadily

In a Zhitong Finance APP notice, China Everbright Water announced that it has recently obtained in Jiangsu two projects: the Phase 3 general contractor and entrusted operation (EPC+O) project for the Huai’an Huaiyin Dongcheng wastewater treatment project (Huaiyin project) and the Phase 1 Phase 2 general contractor and entrusted operation (EPC+O) project for the Jiangyin High-tech Zone wastewater treatment plant (Jiangyin high-tech plant). The back-to-back delivery of the two projects indicates that China Everbright Water has taken a solid step in further cultivating the core areas of the Yangtze River Delta and ramping up in water environment treatment, while also demonstrating the company’s sense of responsibility as a leading environmental services provider in advancing regional water environment governance and protection and supporting high-quality regional development.

Canlong Biochem (03759): Drug-formulation commercialization workshop commissioned; orders from international big pharma; small-molecule CDMO gross margin is expected to improve

Canlong Biochem has released a public announcement of an investor relations activity record. The construction of the drug-formulation commercialization production workshop at the company’s Beijing Second Park has been completed, and in the first quarter of 2026 it signed a strategic cooperation agreement with an international large pharmaceutical company to provide commercialization production services for its first registered oral small-molecule GLP-1 receptor agonist. During the reporting period, the amount of newly signed orders increased by more than 14% year-on-year, with more than 950 new customers and more than 3,300 active customers. Revenue from customers among the global top 20 pharmaceutical companies grew by 29.4% year-on-year. Small-molecule CDMO services involve 1,102 drug molecules or intermediates, including 34 process validation and commercialization-stage projects, and 47 Phase III clinical projects. With the growth in revenue scale of the small-molecule CDMO segment and the advancement of project structure into later stages, the gross margin of small-molecule CDMO services is expected to increase year-on-year compared with 2025. In 2026, the company will maintain steady growth; from the beginning of the year, newly signed orders have continued to show growth momentum, and revenue from clinical research services is expected to remain on an upward trend.

Braintec Extreme Light-B (06681) becomes a strategic cooperation unit of Beijing Frontier Brain-Computer Interface Research Institute; together advance key technologies for clinical translation of brain-computer interface

In a Zhitong Finance APP notice, Braintec Extreme Light-B announced that the group has officially become a strategic cooperation unit of the Beijing Frontier Brain-Computer Interface Research Institute recently. On March 27, 2026, the company’s subsidiary Zhejiang Braintec Extreme Light Medical Technology Co., Ltd. and the Beijing Frontier Brain-Computer Interface Research Institute signed a strategic cooperation agreement on site.

【Stock Picks in Focus】

Hyuge-B (02256): FGFR4 inhibitor irpagratinib (Irpagratinib/ABSK-011) granted orphan drug status by EMA

Hyuge announced that its independently developed highly selective small-molecule FGFR4 inhibitor irpagratinib (Irpagratinib/ABSK-011) has obtained orphan drug designation (ODD) from the European Medicines Agency (EMA) for the treatment of hepatocellular carcinoma (HCC). Currently, irpagratinib is conducting clinical research in multiple regions worldwide; this time, the EMA’s ODD will provide strong support for the product’s clinical development, registration submission, and commercialization process in Europe.

Public information shows that irpagratinib is a highly selective, orally administered small-molecule FGFR4 inhibitor independently developed by Hyuge Pharma. In addition to the EMA orphan drug designation obtained this time, irpagratinib previously also received orphan drug designation (ODD) and fast track designation (FTD) from the U.S. Food and Drug Administration (FDA), as well as breakthrough therapy designation (BTD) from China’s National Medical Products Administration (NMPA).