
(Image source: a16zcrypto)
In its annual outlook, a16z highlights five major areas expected to define the coming year. These domains illustrate how blockchain innovation is expanding beyond experimentation and moving toward deeply integrated, real-world usage. Key areas of focus include on-chain native issuance for RWAs, upgraded global stablecoin payment systems, the rise of autonomous AI agents, advancements in privacy technologies, and new application layers such as prediction markets and “Staked Media.” Collectively, these innovations outline the next stage of open finance and open networks.
The report emphasizes that today’s financial architecture faces structural limitations—limitations that blockchain technology is uniquely positioned to solve. Several key observations shape this viewpoint:
As AI systems interact with on-chain assets and global payment networks, financial activities could increasingly be executed through automated logic, enabling seamless and low-cost movement of value across platforms and borders.
a16z suggests that full-scale asset tokenization could fundamentally expand access to financial tools. As investment instruments transition onto blockchains, users may experience a shift in how wealth is managed:
This combination of tokenized assets and AI-enabled intelligence may pave the way for widespread adoption of customizable, automated financial assistants.
With the expansion of cross-chain applications, privacy is emerging as a critical battleground. a16z believes privacy-focused solutions will play a defining role in the next generation of blockchain infrastructure:
A future version of open finance will require both transparency and personal data protection—a balance that determines how broadly these systems can scale.
The outlook also highlights emerging use cases that could gain significant traction:
These innovations expand the concept of verifiable computation and user-controlled data, creating a network environment where rules become self-enforcing through programmable logic.
As regulatory clarity and technical capabilities advance, crypto systems are positioned to integrate more deeply with global economic infrastructure. In this transition, blockchain networks could:
According to a16z, this convergence marks not just technological evolution, but a large-scale restructuring of the global digital economy.
The a16z annual outlook signals that 2026 represents a turning point where crypto evolves from experimental tools into essential infrastructure. Key domains—RWA issuance, AI-driven systems, privacy technologies, global stablecoin payments, and next-generation applications—are beginning to interconnect and form a unified framework for programmable, verifiable value transfer. As finance, identity, and digital content move onto transparent and trust-minimized systems, the architecture of the open internet is on track to be fundamentally redesigned.





