Wuxi WuXi AppTec New Drug Development Co., Ltd. Notice of the 2025 Annual Shareholders Meeting, the 2026 First A-Share Shareholders Meeting, and the 2026 First H-Share Shareholders Meeting

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Stock Code: 603259 Stock Short Name: WuXi AppTec Announcement No.: Lin 2026-015

Wuxi AppTec New Drug Development Co., Ltd.

Notice of the convening of the 2025 annual general meeting of shareholders, the 2026 first A-share class meeting of shareholders, and the 2026 first H-share class meeting of shareholders

The board of directors of the Company and all directors hereby guarantee that the contents of this announcement do not contain any false records, misleading statements, or material omissions, and assume legal responsibility for the truthfulness, accuracy, and completeness of the contents.

Key Matters for Attention:

● Date of the shareholders’ meeting: April 28, 2026

● Network voting system adopted for this shareholders’ meeting: the Shanghai Stock Exchange shareholders’ meeting network voting system

I. Basic information on convening the meeting

(I) Type and session of the shareholders’ meeting

2025 annual general meeting of shareholders, the 2026 first A-share class meeting of shareholders, and the 2026 first H-share class meeting of shareholders

(II) Convener of the shareholders’ meeting: the board of directors

(III) Voting methods: the voting method adopted for this shareholders’ meeting combines in-person voting and network voting

(IV) Date, time, and venue for the convening of the in-person meeting

Date and time of convening: April 28, 2026 14:00 The 2025 annual general meeting of shareholders, the 2026 first A-share class meeting of shareholders, and the 2026 first H-share class meeting of shareholders will be convened sequentially starting from the time stated above

Venue: Shanghai Waigaoqiao Sheraton Hotel, No. 28 Jilong Road, China (Shanghai) Pilot Free Trade Zone

(V) Network voting system, start and end dates, and voting time.

Network voting system: the Shanghai Stock Exchange shareholders’ meeting network voting system

Start and end time for network voting: from April 28, 2026

to April 28, 2026

Voting time via the Shanghai Stock Exchange network voting system includes the trading time slot on the day of the shareholders’ meeting, i.e., 9:15-9:25, 9:30-11:30, 13:00-15:00; voting time via the internet voting platform is 9:15-15:00 on the day of the shareholders’ meeting.

(VI) Voting procedures for margin trading/securities lending, transfer of shares through refinancing, buyback by agreement, and Shanghai-Hong Kong Stock Connect investors

For voting involving margin trading/securities lending, transfer of shares through refinancing, buyback by agreement-related accounts, and Shanghai-Hong Kong Stock Connect investors, such voting shall be carried out in accordance with《Guidelines for Self-Regulation No. 1—Standardized Operation of Listed Companies of the Shanghai Stock Exchange》and《Hong Kong Securities Clearing Company Limited’s Implementation Guidance for Network Voting by Listed Companies Participating in Shanghai-Hong Kong Stock Connect》and other relevant provisions.

(VII) Matters involving public solicitation of voting rights by shareholders

None

II. Matters to be considered at the meeting

Resolutions proposed for this shareholders’ meeting and types of shareholders entitled to vote

(I) Resolutions proposed for the 2025 annual general meeting of shareholders and types of shareholders entitled to vote

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The 2025 annual general meeting of shareholders will also hear the《2025 Annual Independent Director’s Work Report》.

(II) Resolutions proposed for the 2026 first A-share class meeting of shareholders and types of shareholders entitled to vote

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(III) Resolutions proposed for the 2026 first H-share class meeting of shareholders and types of shareholders entitled to vote

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1. The time of prior disclosure of each resolution and the disclosure media

The above resolutions have been approved at the 27th meeting of the third session of the board of directors held on March 23, 2026 by our Company and the 2025 annual meeting of the board of directors. For the specific contents of the resolutions of the meeting, please refer to the relevant announcements published by the Company on March 24, 2026 on the website of the Shanghai Stock Exchange (www.sse.com.cn) and in the designated information disclosure media. The meeting materials for this meeting will be announced separately.

2. Special resolutions: Resolution Items 8, 16, and 17 of the 2025 annual general meeting of shareholders; Resolution Item 2 of the 2026 first A-share class meeting of shareholders; Resolution Item 2 of the 2026 first H-share class meeting of shareholders.

3. Resolutions for which separate counting of votes will be conducted for small and medium investors: Resolution Items 2, 3, 6, 7, 11, 12, 14, 18.00, and 19.00.

4. Resolutions involving avoidance of voting by related shareholders: Resolution Items 11, 12, 13, 14, and 15 of the 2025 annual general meeting of shareholders; Resolution Item 1 of the 2026 first A-share class meeting of shareholders; Resolution Item 1 of the 2026 first H-share class meeting of shareholders.

Names of related shareholders required to avoid voting: the shareholders whose shareholding, as recorded on the stock registration record date for this shareholders’ meeting, is intended to be the reward beneficiaries under the 2025 and 2026 H-share Incentive Trust Plan, and the shareholders of our Company controlled by them or authorized by them to vote, as well as the directors of the Company and the shareholders of our Company whose voting is controlled by them.

5. Resolutions involving preferred shareholders’ participation in voting: None

III. Voting precautions for shareholders’ meetings

(I) If shareholders of the Company exercise their voting rights through the shareholders’ meeting network voting system of the Shanghai Stock Exchange, they may vote either by logging in to the trading system voting platform (via the trading terminal of the securities company designated for trading) or by logging in to the internet voting platform (website: vote.sseinfo.com). When shareholders first log in to the internet voting platform to vote, they need to complete shareholder identity verification. For specific procedures, please see the instructions on the website of the internet voting platform.

(II) If the number of votes cast by a shareholder exceeds the number of election votes it holds, or if, in difference-based elections, votes are cast exceeding the number of persons to be elected, the election votes cast for that resolution shall be deemed invalid.

(III) If the same voting rights are exercised repeatedly through in-person voting, the Shanghai Stock Exchange shareholders’ meeting network voting platform, or other methods, the result of the first vote shall prevail.

(IV) Shareholders holding multiple shareholders’ accounts may exercise voting rights in the total quantity of the same class of ordinary shares and the same type of preferred shares held across all shareholders’ accounts under their names.

Shareholders holding multiple shareholders’ accounts and participating in the shareholders’ meeting network voting through the Shanghai Stock Exchange network voting system may participate through any one of their shareholders’ accounts. After voting, it shall be deemed that the voting ballots with the same opinion have been cast separately for the same class of ordinary shares and the same type of preferred shares under all of their shareholders’ accounts.

For shareholders holding multiple shareholders’ accounts who cast votes repeatedly through multiple shareholders’ accounts, the voting opinions for the same class of ordinary shares and the same type of preferred shares under all of their shareholders’ accounts shall be determined separately by the first voting results for each class and each type of shares.

(V) Shareholders can submit only after voting on all resolutions.

(VI) For shareholders’ voting method to elect directors and independent directors using cumulative voting, please see Appendix 3.

(VII) A-share shareholders participating in network voting who cast votes at the Company’s 2025 annual general meeting of shareholders shall be deemed to have cast the same voting for the corresponding resolutions at the Company’s 2026 first A-share class meeting of shareholders. A-share shareholders attending the in-person meeting shall vote separately at the Company’s 2025 annual general meeting of shareholders and the Company’s 2026 first A-share class meeting of shareholders, respectively.

IV. Persons eligible to attend the meeting

(I) A-share shareholders of the Company whose names are recorded in the Shanghai branch of China Securities Depository and Clearing Co., Ltd. as of the close of business on the shareholders’ meeting record date shall be entitled to attend the 2025 annual general meeting of shareholders and the 2026 first A-share class meeting of shareholders (for details, see the table below), and may appoint an agent to attend the meeting and vote in writing. Such agent need not be a shareholder of the Company.

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(II) Directors and senior management personnel of the Company.

(III) Lawyers engaged by the Company.

(IV) Other persons.

V. Registration methods for the meeting

Shareholders meeting the above attendance conditions who wish to attend the in-person meeting shall provide the following registration materials:

1. Corporate shareholders: If a corporate shareholder’s legal representative attends the meeting, he/she shall bring the business license, the corporate shareholder’s stock account card, his/her own identity card, and valid documentation that can demonstrate that he/she has the status of legal representative; if an authorized agent attends the meeting, the agent shall bring the business license, the corporate shareholder’s stock account card, his/her own identity card, and the written authorization letter issued by the legal representative of the corporate shareholder in accordance with law (see Appendix 1 and Appendix 2).

2. Individual shareholders: If an individual shareholder attends the meeting in person, he/she shall bring his/her own identity card or other valid documents that can indicate identity and the stock account card; if an authorized agent attends the meeting on behalf of an individual shareholder, the agent shall also bring the agent’s valid identity documents and the shareholders’ authorization letter (see Appendix 1 and Appendix 2).

3. For margin trading and securities lending investors attending the meeting, they shall bring the business license of the securities company related to margin trading and securities lending, the securities account proof, and the authorization letter issued by them to the investors; if the investor is an individual, he/she shall also hold his/her own identity card or other valid documents that can indicate his/her identity; if the investor is an entity, he/she shall also hold the entity’s business license, the identity card of the personnel attending the meeting, and the authorization letter issued by the entity’s legal representative (see Appendix 1 and Appendix 2).

4. Shareholders who choose network voting may participate directly in voting at the shareholders’ meeting through the Shanghai Stock Exchange system or the internet voting platform.

(II) Registration time for the in-person meeting

April 28, 2026 (Tuesday) 13:30-14:00. After the above time period, registration for attendance at the in-person meeting will no longer be handled.

(III) Venue for registration for the in-person meeting

Shanghai Waigaoqiao Sheraton Hotel, No. 28 Jilong Road, China (Shanghai) Pilot Free Trade Zone.

VI. Other matters

1. Meeting affairs contact: Han Min

2. Contact phone number: 021-20663091

3. Fax number: 021-50463093

4. Email: ir@wuxiapptec.com

5. Contact address: No. 288 Futong Middle Road, Pudong New Area, Shanghai

6. Accommodation and transportation expenses for shareholders attending this meeting and their proxies shall be borne by themselves.

7. For H-share shareholders’ attendance matters, please refer to the Company’s announcement on the website of The Stock Exchange of Hong Kong Limited (

Notice is hereby given.

Board of Directors of Wuxi AppTec New Drug Development Co., Ltd.

March 25, 2026

Appendix 1: Authorization letter for the 2025 annual general meeting of shareholders

Appendix 2: Authorization letter for the 2026 first A-share class meeting of shareholders

Appendix 3: Explanation of the voting method for electing directors and independent directors using cumulative voting

Appendix 1: Authorization letter for the 2025 annual general meeting of shareholders

Authorization Letter for the 2025 Annual General Meeting of Shareholders

Wuxi AppTec New Drug Development Co., Ltd.:

I hereby appoint Mr./Ms. to represent this unit (or myself) and attend the Company’s 2025 annual general meeting of shareholders to be held on April 28, 2026, and to exercise voting rights on my behalf.

Number of ordinary shares held by the appointor:

Number of preferred shares held by the appointor:

Account number of the shareholder:

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Signature (and seal) of the appointor: Signature of the proxy:

ID number of the appointor: ID number of the proxy:

Date of authorization: Year Month Day

Notes:

The appointor shall select one of “for,” “against,” or “abstain” in this authorization letter and mark it with “√”. If the appointor has not given specific instructions in this authorization letter, the proxy shall have the right to vote according to his/her own discretion.

Appendix 2: Authorization letter for the 2026 first A-share class meeting of shareholders

Authorization Letter for the 2026 First A-share Class Meeting of Shareholders

Wuxi AppTec New Drug Development Co., Ltd.:

I hereby appoint Mr./Ms. to represent this unit (or myself) and attend the Company’s 2026 first A-share class meeting of shareholders to be held on April 28, 2026, and to exercise voting rights on my behalf.

Number of ordinary shares held by the appointor:

Number of preferred shares held by the appointor:

Shareholder account number:

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Signature (and seal) of the appointor: Signature of the proxy:

ID number of the appointor: ID number of the proxy:

Date of authorization: Year Month Day

Notes:

The appointor shall select one of “for,” “against,” or “abstain” in this authorization letter and mark it with “√”. If the appointor has not given specific instructions in this authorization letter, the proxy shall have the right to vote according to his/her own discretion.

Appendix 3: Explanation of the voting method for electing directors and independent directors using cumulative voting

I. The election of directors at the shareholders’ meeting and the election of independent directors are each numbered separately as groups of proposals. Investors shall vote for each candidate under each proposal group.

II. The number of shares submitted represents the number of election votes. For each proposal group, one share held by a shareholder grants a total number of voting votes equal to the number of directors to be elected under that proposal group. For example, if a shareholder holds 100 shares of a listed company, and the meeting elects 10 directors, and there are 12 director candidates, then for the proposal group for election of directors, the shareholder has election votes of 1,000 shares.

III. Shareholders shall vote within the number of election votes for each proposal group. Shareholders vote according to their own intention. They may concentrate all election votes on a single candidate, or distribute them to different candidates in any combination. After voting ends, the votes cast shall be cumulatively calculated for each resolution item separately.

IV. Example:

Suppose a listed company holds a shareholders’ meeting adopting cumulative voting to re-elect directors, where 5 directors are to be elected and there are 6 director candidates; and 2 independent directors are to be elected, with 3 independent director candidates. The matters requiring vote and approval are as follows:

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At the closing of trading on the record date for shareholding, a certain investor holds 100 shares of this company. Using cumulative voting, he/she has 500 voting rights under proposal 4.00 “Proposal on the Election of Directors,” and 200 voting rights under proposal 5.00 “Proposal on the Election of Independent Directors.”

Within the limit of 500 votes, this investor may cast a vote on proposal 4.00 according to his/her own intention. He/she may either give all 500 votes to a single candidate, or distribute the votes among any candidates in any combination.

As shown in the table:

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