MDA 2026: Biogen, Sarepta, Edgewise Address Muscle Disorders

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The 2026 Muscular Dystrophy Association (MDA) conference highlighted new developments from Biogen, Sarepta, and Edgewise in muscular dystrophy treatment. Biogen’s salanersen showed significant reduction in a key SMA biomarker and is advancing to Phase 3. Edgewise Therapeutics presented positive long-term functional data for its Becker muscular dystrophy drug, sevasemten, from its MESA study, contributing to its ongoing pivotal trial. Sarepta Therapeutics provided a post-hoc analysis for its Duchenne muscular dystrophy exon-skippers, Vyondys 53 and Amondys 45, to support their full FDA approval and also shared positive 3-year data for its gene therapy Elevidys in ambulatory patients.

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