Bio Protocol (BIO), as a curation and liquidity protocol for Decentralized Science (DeSci), has been accelerating biotechnology development since its inception. As of 2025, BIO's market capitalization has reached $122,628,371, with a circulating supply of approximately 1,825,370,228 tokens, and a price hovering around $0.06718. This asset, known as a "biotechnology accelerator," is playing an increasingly crucial role in collectively funding, building, and owning tokenized biotech projects and intellectual property.
This article will comprehensively analyze BIO's price trends from 2025 to 2030, combining historical patterns, market supply and demand, ecosystem development, and macroeconomic factors to provide professional price predictions and practical investment strategies for investors.
As of November 16, 2025, BIO is trading at $0.06718, with a 24-hour trading volume of $382,832. The token has experienced a 1% decrease in the last 24 hours. BIO's market capitalization stands at $122,628,371, ranking it 343rd in the cryptocurrency market. The circulating supply is 1,825,370,228.24 BIO tokens, which represents 54.98% of the total supply of 3,320,000,000 BIO. The token is currently trading 93.84% below its all-time high and 131.18% above its all-time low. The market sentiment for BIO appears bearish, with negative price trends across various timeframes, including a 14.37% decrease in the past week and a 20.69% decline over the last month.
Click to view the current BIO market price

2025-11-16 Fear and Greed Index: 10 (Extreme Fear)
Click to view the current Fear & Greed Index
The crypto market is gripped by extreme fear, with the index plummeting to 10. This level of pessimism often precedes significant market movements. Historically, such extreme fear has presented potential buying opportunities for long-term investors. However, caution is advised as market volatility may persist. Traders should consider risk management strategies and stay informed about market developments. Remember, market sentiment can shift rapidly, and it's crucial to make informed decisions based on thorough research and personal risk tolerance.

The address holdings distribution chart for BIO reveals a highly concentrated ownership structure. The top address holds a staggering 45% of the total supply, while the top five addresses collectively control 77.09% of all BIO tokens. This level of concentration raises concerns about the token's decentralization and potential market manipulation risks.
Such a concentrated distribution can significantly impact market dynamics. The top holders have substantial influence over price movements, potentially leading to increased volatility. Any large-scale transactions by these addresses could cause significant price fluctuations. Moreover, this concentration may deter smaller investors, fearing vulnerability to whale movements.
This distribution pattern suggests a relatively low degree of decentralization for BIO. While some concentration is common in newer projects, this level is particularly high. It indicates a need for broader token distribution to enhance market stability and reduce manipulation risks. Investors should monitor these top addresses for any significant changes that could signal major market shifts.
Click to view the current BIO Holdings Distribution

| Top | Address | Holding Qty | Holding (%) |
|---|---|---|---|
| 1 | 0x0d2a...7d2ef4 | 1378437.43K | 45.00% |
| 2 | 0xd9c6...e8a1ab | 541491.92K | 17.67% |
| 3 | 0xf977...41acec | 203471.32K | 6.64% |
| 4 | 0xf91a...56f40c | 129799.59K | 4.23% |
| 5 | 0xf3dc...458a43 | 108800.00K | 3.55% |
| - | Others | 701157.47K | 22.91% |
| 年份 | 预测最高价 | 预测平均价格 | 预测最低价 | 涨跌幅 |
|---|---|---|---|---|
| 2025 | 0.08137 | 0.06725 | 0.05111 | 0 |
| 2026 | 0.09586 | 0.07431 | 0.05722 | 10 |
| 2027 | 0.11402 | 0.08509 | 0.05956 | 26 |
| 2028 | 0.13937 | 0.09955 | 0.09159 | 47 |
| 2029 | 0.16247 | 0.11946 | 0.08482 | 77 |
| 2030 | 0.18466 | 0.14096 | 0.10995 | 109 |
(1) Long-term Holding Strategy
(2) Active Trading Strategy
(1) Asset Allocation Principles
(2) Risk Hedging Solutions
(3) Secure Storage Solutions
BIO presents a unique opportunity in the DeSci space with potential long-term value, but faces short-term volatility and regulatory uncertainties. The project's success depends on adoption within the scientific community and technological advancements.
✅ Beginners: Consider small, regular investments to build a position over time ✅ Experienced investors: Implement a balanced approach with strategic entry and exit points ✅ Institutional investors: Conduct thorough due diligence and consider BIO as part of a diversified crypto portfolio
Cryptocurrency investments carry extremely high risks, and this article does not constitute investment advice. Investors should make decisions carefully based on their own risk tolerance and are advised to consult professional financial advisors. Never invest more than you can afford to lose.
While predicting exact prices is challenging, BIO has potential to reach $1 given its innovative protocol and growing adoption in the Web3 space. Market conditions and project developments will be key factors.
Yes, BIO could be a good investment. Its innovative blockchain solutions and growing adoption in the biotech sector suggest potential for significant value growth in the coming years.
Based on current trends and market analysis, BIO coin is predicted to reach $5 to $7 by 2030, potentially offering significant returns for long-term investors.
Yes, BIO shows strong potential as an investment in the Web3 space, with its innovative technology and growing adoption in the crypto market.
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